
Hello beautiful people, what’s better than Salmon DNA? Salmon DNA with a collagen biostimulator, at the same time. Today’s tip of the day is about why treating the skin and the tissue together can give a result that neither treatment reaches on its own.
Dr Rami Haidar | 4th April 2025 | Excellence Medical Boutique, Dubai
Salmon DNA and collagen biostimulators work on different layers and address different concerns. Salmon DNA, the patient-friendly name for polynucleotides, is a regenerative skin treatment. It supports repair, hydration and elasticity within the skin itself, which shows as improved texture and a healthier-looking surface.
Collagen biostimulators work deeper. They prompt the tissue to produce new collagen over the following weeks, gradually improving firmness and support. Neither treatment is a filler, and neither creates immediate volume.
Combining them means working on the skin and the tissue within one plan. Many patients have both concerns at once: dull or dehydrated skin on the surface, and a gradual loss of firmness beneath it. Treating only one layer leaves the other unchanged. Used together, the polynucleotides support skin quality while the biostimulator rebuilds support, so the face looks fresher and subtly lifted rather than filled.
In the video, Dr Rami treats both in the same session at Excellence Medical Boutique, using a cannula to place the biostimulator through the midface, where loss of support often shows first. The treatment is generally well tolerated, with numbing used where needed. Results build over several weeks as the skin repairs and new collagen forms, so this combination suits patients who want gradual improvement rather than an overnight change.
Not everyone needs both. Patients whose concern is purely skin quality may do well with polynucleotides alone, and where structural volume has been lost, dermal filler may be part of the discussion. The combination is chosen after assessment, not by default.
Yes, for suitable patients the two can be combined in the same session. They work on different layers, with Salmon DNA supporting skin quality and the biostimulator encouraging collagen for firmness and support. Whether combining is right for you is decided at consultation.
Salmon DNA, or polynucleotides, is a regenerative treatment that supports repair, hydration and elasticity in the skin. A collagen biostimulator works deeper, prompting the tissue to produce new collagen that improves firmness over time. One focuses mainly on skin quality and the other on tissue support.
Many patients have both a skin quality concern and a gradual loss of firmness. Treating only one layer leaves the other unchanged, so the result can look incomplete. Combining them addresses both in one plan while still producing a subtle, natural-looking change.
Most patients find it well tolerated. Numbing cream can be used, and the biostimulator is often placed with a blunt cannula, which reduces the number of entry points. Some tenderness, swelling or small bruises can occur afterward and usually settle within a few days.
Some patients notice improved skin hydration within a few weeks. Firmness from new collagen develops more slowly, usually over two to three months. Results vary with age, skin quality and the treatment plan agreed.
Many patients have a short course, often two or three sessions spaced several weeks apart, although some need fewer. The number depends on your starting skin quality and the degree of laxity. Dr Rami confirms the plan after assessment.
Good candidates often have dull or dehydrated skin together with early loss of firmness, and want gradual, natural-looking improvement rather than added volume. It may not suit patients who need significant structural correction, or those with certain allergies or active skin infection. Suitability is decided at consultation.
If your skin looks tired and you are starting to notice a loss of firmness, book a consultation with Dr Rami Haidar at Excellence Medical Boutique in Jumeirah, Dubai. The assessment looks at skin quality and tissue support separately, so your plan reflects whether Salmon DNA, a collagen biostimulator or the two together are right for you.

Located in the heart of Jumeirah, Dubai, Excellence Medical Boutique is more than a clinic, it’s a destination. A sanctuary where innovation, expertise and care come together to enhance your natural beauty and confidence. Excellence Medical Boutique is conveniently located on 197 Jumeira St, Jumeirah, Jumeirah 1, Dubai. This makes it easy for patients travelling from across Dubai to visit for consultation and treatment.