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Polynucleotides vs Fillers | Which Treatment Is Right for You?

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Discover the difference between fillers and Polynucleotides at Excellence Medical Boutique, Dubai. Natural skin and structure enhancement.

Polynucleotides vs Fillers | Which Treatment Is Right for You?

Hello beautiful people, today I want to talk about one of the most common questions I hear in clinic, ‘what’s the difference between fillers and Polynucleotides?’

While both treatments are made from hyaluronic acid, the key difference lies in how that HA is structured.
As Dr Rami explains, “Cross-linked HA gives support and structure, that’s what we use in fillers. Non–cross-linked HA spreads evenly through the skin, that’s what we use in boosters for hydration and glow.”

So, while fillers help to shape and define, Polynucleotides and boosters focus on improving skin quality from within, enhancing hydration, elasticity, and radiance.

In Dubai’s climate, where our skin constantly faces sun exposure, air conditioning, and dryness, understanding this difference is essential. The goal isn’t always more volume, it’s about choosing what your skin truly needs to stay healthy, supple, and balanced.

Dr Rami Haidar

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Polynucleotides vs Fillers: What’s the Difference?

At Excellence Medical Boutique, patients often ask which injectable is best for their skin, fillers and boosters While both improve facial appearance, they serve completely different purposes.

Fillers (Cross-linked Hyaluronic Acid):

  • Created using cross-linked HA, which makes the gel firm and supportive.

  • Designed to lift, shape, and contour, restoring structure to areas like the cheeks, chin, and jawline.

  • Provides immediate volume and visible definition right after treatment.

  • Ideal for patients wanting to enhance features or correct volume loss with natural precision.

 

Polynucleotides and Boosters (Non–Cross-linked, Regenerative Treatments):

  • These treatments use non–cross-linked hyaluronic acid or Polynucleotides (Salmon DNA) to rejuvenate and hydrate the skin from within.

  • Unlike fillers, which add volume, boosters and Polynucleotides focus on improving skin texture, elasticity, and glow.

  • They activate natural cell repair, stimulate new collagen production, and enhance overall skin quality.

  • Results build gradually over a series of sessions, leaving the skin smoother, firmer, and deeply hydrated.

  • Ideal for patients who want to refresh tired, dull, or dehydrated skin without changing facial shape or structure.

Could They Work Together?

While fillers define structure, Polynucleotides rebuild quality. Many patients in Jumeirah and across Dubai combine the two, fillers for contour, boosters for glow, achieving balance between shape and skin vitality.

The right choice always depends on your anatomy, age, and goals, which Dr Rami Haidar carefully assesses during each consultation to create a personalised plan that feels both natural and refined.

Who It’s For?

These treatments suit a wide range of patients:

  • Those wanting to restore volume or contour the face naturally.

  • Individuals noticing dullness, dehydration, or fine lines from Dubai’s sun and air conditioning.

  • Anyone seeking a balanced, refreshed look without surgery or downtime.

  • Perfect for patients who prefer a subtle, healthy glow over dramatic change.

Overall:

  • Fillers → Add structure, lift, and contour using cross-linked HA for immediate definition.

  • Boosters & Polynucleotides → Improve hydration, texture, and elasticity with non–cross-linked HA or regenerative DNA fragments.

  • Combined Approach → Shape and rejuvenate — creating balance between skin health and facial structure.

 

Why Understanding the Difference Matters in Dubai

In Dubai’s climate, where high temperatures, strong sunlight, and constant air conditioning can dehydrate and stress the skin, knowing the difference between fillers and boosters is essential.

Many patients assume all injectables do the same thing, but that’s not true. Fillers restore structure and contour, helping to redefine facial balance, while Polynucleotides and skin boosters target hydration and repair, rebuilding skin health from within.

By understanding what each injectable actually does, patients can make informed choices and achieve results that look natural, not exaggerated. Whether your goal is sharper definition or smoother, more luminous skin, the treatment should always be guided by your individual anatomy and lifestyle.

At Excellence Medical Boutique, Dr Rami Haidar focuses on matching each patient’s needs with the right approach, ensuring every result feels precise, elegant, and completely personal.

Results and Expectations:

Fillers (Cross-linked HA):

  • Immediate results: volume and contour are visible straight after treatment.

  • Help restore symmetry, lift, and structure in areas such as the cheeks, chin, and jawline.

  • Results typically last 12 to 18 months, depending on the product used and individual metabolism.

  • Minimal downtime; mild swelling or tenderness may occur but settles within 24 hours.

Polynucleotides & Boosters (Non–Cross-linked):

  • Gradual results that develop over 3–6 weeks as collagen and elastin production increases.

  • Improve hydration, texture, and skin resilience, giving a healthy, radiant glow.

  • Best results are achieved after 2–3 sessions, spaced a few weeks apart.

  • Results can last up to 12 months and improve with regular maintenance.

The goal isn’t just to improve appearance, it’s to restore balance between structure and skin health in a way that feels natural and timeless.

All treatments are doctor-led, with minimal downtime and individually tailored after consultation. Costs are based on your skin’s unique needs and goals.

Why Patients in Jumeirah Choose These Treatments:

Patients in Jumeirah often choose either fillers or boosters because they want results that look refined, not transformed. These treatments appeal to people who value subtle enhancement and trust a clinical approach that prioritises balance and authenticity.

Some patients visit Excellence Medical Boutique looking to restore definition or contour with fillers; while others want to repair, hydrate, and strengthen their skin with Polynucleotides or boosters. The decision depends entirely on what the skin needs, not on following trends or routines.

As Dr Rami often explains, the best results come from listening to the skin. Each face tells its own story, some need structure, some need regeneration. By tailoring the approach to anatomy, age, and lifestyle, Dr Rami ensures that every treatment enhances natural beauty while preserving facial harmony.

This personalised approach is why so many patients in Dubai trust Excellence Medical Boutique, they leave feeling confident, refreshed, and completely themselves.

Safety and Expertise Matter:

At Excellence Medical Boutique, safety is the foundation of every procedure. Dr Rami Haidar takes an anatomy-led approach, ensuring precision, symmetry, and minimal risk in all injectable treatments.

Only FDA-approved, high-quality products are used, whether it’s cross-linked hyaluronic acid for structure or regenerative Polynucleotides for skin quality. Each injection point is planned according to your facial anatomy to maintain balance and natural movement.

Side effects such as mild swelling or redness are rare and short-lived, typically resolving within 24 hours. Aftercare is simple: keep the area clean, avoid intense heat or exercise for the first day, and always use sunscreen when outdoors.

Dr Rami believes that expert technique and careful assessment are what truly separate aesthetic medicine from trend-based procedures. His focus is on precision, transparency, and patient trust, ensuring every result looks elegant and effortless.

Aftercare is simple:

  • Avoid touching or massaging the area for 24 hours

  • Skip saunas, steam rooms, or strenuous exercise for one day

  • Keep the skin clean and protected with SPF

Temporary swelling or tenderness is normal and usually resolves within 24 hours. When performed by a skilled injector, jawline sculpting is one of the safest, most effective ways to restore definition and contour.

Dr Rami’s approach combines surgical precision with an artistic eye, ensuring results that are natural, refined, and true to each patient’s individuality.

How much do Polynucleotides and Filler Treatments cost?

The cost of treatments at Excellence Medical Boutique depends on the areas treated, the number of sessions and the product used. After your consultation, you will have a clear plan and pricing. Dr Rami’s focus is always on trust, transparency and gradual transformation, never rushed or overdone.

Your Journey to Naturally Balanced Skin Starts at Excellence Medical Boutique

Whether you’re looking to restore volume with fillers or rejuvenate skin quality with Polynucleotides, the goal is the same, results that enhance your natural beauty, not alter it.
It’s about understanding your skin’s needs, your anatomy, and your lifestyle, then designing a treatment plan that delivers confidence and balance in the most natural way possible.

At Excellence Medical Boutique in Jumeirah, Dubai, every procedure is doctor-led, using an anatomy-based approach to create results that are subtle, symmetrical, and elegant.

If you’re ready to explore fillers or Polynucleotide treatments in Dubai, I’d love to welcome you to Excellence Medical Boutique and create a personalised plan that helps your skin look and feel its absolute best.

– Dr Rami Haidar

Disclaimer: The information on this page is for general educational purposes only and should not be taken as medical advice. All treatments on www.docrami.com are subject to a thorough consultation and suitability assessment with our expert clinical team.

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Polynucleotides and Fillers Before and After

Before and after photos are one of the best ways to understand what these treatments can achieve. During consultation at Excellence Medical Boutique, patients often review filler and Polynucleotide before and after results to see how structure and skin quality can be enhanced — always with a natural finish.

Fillers deliver immediate improvement in contour and definition, refining features such as the jawline, chin, or cheeks while maintaining balance and proportion.

Polynucleotides, on the other hand, offer a gradual transformation — skin becomes smoother, more hydrated, and more luminous with each session as natural collagen and elastin production increases.

While every result is unique, most patients notice their skin looks fresher and healthier, with subtle yet visible refinement that feels completely their own.

See More Results
Before
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After
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After
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Read Dr Rami’s Reviews at Excellence Medical Boutique

I love excellence Medical boutique ! Let’s start by saying this place is so aesthetically pleasing , they will welcome you with a nice variety of tea or coffee… the receptionists are exceptionally friendly and professional… they make sure you are in great health before any treatment by a check up with the in house nurse and then you’ll proceed to see Dr. Rami and his professional team… I really had great results with my Salmon DNA under eyes ! Immediately noticed the difference! HIGHLY RECOMMEND!!
Natacha Jaraba
Natacha Jaraba
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I had such an exceptional experience with Dr.Rami Haidar. The results are beyond my expectations—natural, subtle, and refreshing. I’ve had so many compliments on how glowing and youthful my skin looks, without anyone guessing I had a treatment done. Dr.Rami truly has an eye for detail and delivers results that enhance your features beautifully.

I highly recommend Dr.Rami to anyone considering aesthetic treatments. Their expertise, care, and warm approach make all the difference. I wouldn’t trust anyone else with my face!

Dr. Rami Haider was warm, attentive, and made me feel very comfortable throughout the entire process. His professionalism and skill really showed, and I felt I was in safe hands. I’m very happy with my experience and would highly recommend him to anyone considering treatment
Fatma A
Fatma A
Dr. Rami is truly the best doctor in the world. Not only is he a master at what he does, but he’s also one of the kindest and most genuine people I’ve ever met. His work speaks for itself every result is natural, thoughtful, and beautifully done. I’ve always felt safe understood and in expert hands. So grateful to be treated by someone who combines talent, precision and such a big heart. Truly one of a kind
Mahmoud Abaza
Mahmoud Abaza
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Fillers & Boosters, Frequently Asked Questions

What is the main difference between fillers and Polynucleotides?

Fillers use cross-linked hyaluronic acid to add shape, lift, and contour, while Polynucleotides are regenerative injectables that restore skin quality, hydration, and elasticity. Fillers create volume immediately; Polynucleotides improve the skin gradually from within.

How long do results last?

Filler results usually last 12–18 months, depending on the product and treatment area. Polynucleotide results build over time and can last 6–12 months, improving with regular maintenance sessions.

Which treatment is best for me?

It depends on your goals. Choose fillers if you want to restore contour or definition, and Polynucleotides if you want healthier, smoother, more hydrated skin. Dr Rami Haidar assesses your anatomy and lifestyle to recommend the right option during consultation.

Are these treatments safe?

Yes. At Excellence Medical Boutique, only FDA-approved, premium products are used. Procedures are performed using an anatomy-led approach to minimise risk. Mild redness or swelling may occur briefly after injection.

Does it hurt?

Discomfort is minimal and numbing can be applied if needed.

Can fillers and Polynucleotides be combined?

Yes! When performed strategically, both can complement each other. Fillers define facial shape, while Polynucleotides improve the skin’s tone and texture, resulting in balanced, natural rejuvenation.

Is there downtime after treatment?

Downtime is minimal. Most patients return to normal activities the same day. Any mild swelling or redness typically subsides within 24–48 hours.

Are Polynucleotides the same as skin boosters?

Not exactly. Both improve hydration, but Polynucleotides go deeper, stimulating collagen and elastin to repair the skin’s structure, whereas traditional skin boosters focus on surface hydration and glow.

How much do these treatments cost in Dubai?

Pricing depends on the number of sessions, treated areas, and chosen products. After consultation, Dr Rami provides a clear, personalised plan unique to every patient

Book a consultation with Dr Rami in Dubai at Excellence Medical Boutique

Excellence Medical Boutique is conveniently located at 197 Jumeirah Street, Jumeirah, Dubai easily accessible from Jumeirah 1 & 2, Al Wasl Road, Downtown Dubai and Dubai Marina. If you’re coming from other parts of the city, we’re just a short drive from Business Bay, DIFC, Al Safa and Umm Suqeim.

Excellence Medical Boutique
197 Jumeira St Jumeirah Dubai
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